Invention Grant
- Patent Title: Methods of treating or diagnosing conditions associated with elevated IL-6 using anti-IL-6 antibodies or fragments
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Application No.: US12624778Application Date: 2009-11-24
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Publication No.: US08900580B2Publication Date: 2014-12-02
- Inventor: Leon Garcia-Martinez , Anne Elisabeth Carvalho Jensen , Katie Olson , Ben Dutzar , John Latham , Brian Kovacevich , Jeffrey T. L. Smith , Mark Litton , Randall Schatzman
- Applicant: Leon Garcia-Martinez , Anne Elisabeth Carvalho Jensen , Katie Olson , Ben Dutzar , John Latham , Brian Kovacevich , Jeffrey T. L. Smith , Mark Litton , Randall Schatzman
- Applicant Address: US NV Las Vegas
- Assignee: AlderBio Holdings LLC
- Current Assignee: AlderBio Holdings LLC
- Current Assignee Address: US NV Las Vegas
- Agency: LeClairRyan, a professional corporation
- Agent Robin L. Teskin
- Main IPC: A61K39/395
- IPC: A61K39/395 ; A61K51/10 ; A61K49/00 ; A61K39/00 ; C07K16/24 ; C12P21/08 ; C12N15/63

Abstract:
The invention relates to the use of anti-IL-6 antibodies or antibody fragments containing a specific epitopic specificity to treat conditions involving elevated Il-6. In some embodiments the anti-IL-6 antibodies contain specific CDRs.
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