Invention Grant
US08900589B2 Anthracycline derivative conjugates, process for their preparation and their use as antitumor compounds
有权
蒽环类衍生物缀合物，其制备方法及其作为抗肿瘤化合物的用途
- Patent Title: Anthracycline derivative conjugates, process for their preparation and their use as antitumor compounds
- Patent Title (中): 蒽环类衍生物缀合物，其制备方法及其作为抗肿瘤化合物的用途
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Application No.: US12502433Application Date: 2009-07-14
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Publication No.: US08900589B2Publication Date: 2014-12-02
- Inventor: Italo Beria , Michele Caruso , John A. Flygare , Vittoria Lupi , Rita Perego , Paul Polakis , Andrew Polson , Matteo Salsa , Susan D. Spencer , Barbara Valsasina , Robert L. Cohen
- Applicant: Italo Beria , Michele Caruso , John A. Flygare , Vittoria Lupi , Rita Perego , Paul Polakis , Andrew Polson , Matteo Salsa , Susan D. Spencer , Barbara Valsasina , Robert L. Cohen
- Applicant Address: US CA South San Francisco
- Assignee: Genetech, Inc.
- Current Assignee: Genetech, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Genetech, Inc.
- Agent Alex Andrus
- Main IPC: A61K47/48
- IPC: A61K47/48 ; A61K39/00 ; C07K16/28 ; C07K14/00
Abstract:
The present invention relates to conjugates of therapeutically useful anthracyclines with carriers such as polyclonal and monoclonal antibodies, proteins or peptides of natural or synthetic origin; methods for their preparation, pharmaceutical composition containing them and use thereof in treating certain mammalian tumors.
Public/Granted literature
- US20100034837A1 ANTHRACYCLINE DERIVATIVE CONJUGATES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOR COMPOUNDS Public/Granted day:2010-02-11
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