Invention Grant
- Patent Title: Binding proteins inhibiting the VEGF-A receptor interaction
- Patent Title (中): 结合蛋白抑制VEGF-A受体相互作用
-
Application No.: US13126821Application Date: 2009-11-03
-
Publication No.: US08901076B2Publication Date: 2014-12-02
- Inventor: Hans Kasper Binz , Patrik Forrer , Michael Tobias Stumpp
- Applicant: Hans Kasper Binz , Patrik Forrer , Michael Tobias Stumpp
- Applicant Address: CH Schlieren
- Assignee: Molecular Partner AG
- Current Assignee: Molecular Partner AG
- Current Assignee Address: CH Schlieren
- Agency: Wenderoth, Lind & Ponack. L.L.P.
- Priority: EP08168166 20081103
- International Application: PCT/EP2009/064483 WO 20091103
- International Announcement: WO2010/060748 WO 20100603
- Main IPC: A61K38/16
- IPC: A61K38/16 ; C07K14/00 ; C07K14/47 ; A61K38/00
Abstract:
The present invention relates to binding proteins specific for VEGF-A, in particular to recombinant binding proteins comprising a binding domain, which inhibits VEGF-Axxx binding to VEGFR-2. Examples of such binding proteins are proteins which comprise an ankyrin repeat domain with the desired binding specificity. The binding proteins are useful in the treatment of cancer and other pathological conditions, e.g. eye diseases such as age-related macular degeneration.
Public/Granted literature
- US20110207668A1 BINDING PROTEINS INHIBITING THE VEGF-A RECEPTOR INTERACTION Public/Granted day:2011-08-25
Information query
IPC分类:
