Invention Grant
US08901120B2 Substituted N-phenylpyrimidin-2-amine analogs as inhibitors of the Axl kinase
有权
取代的N-苯基嘧啶-2-胺类似物作为Axl激酶的抑制剂
- Patent Title: Substituted N-phenylpyrimidin-2-amine analogs as inhibitors of the Axl kinase
- Patent Title (中): 取代的N-苯基嘧啶-2-胺类似物作为Axl激酶的抑制剂
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Application No.: US13436910Application Date: 2012-03-31
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Publication No.: US08901120B2Publication Date: 2014-12-02
- Inventor: David J. Bearss , Hariprasad Vankayalapati , Alexis Mollard , Steven L. Warner , Sunil Sharma
- Applicant: David J. Bearss , Hariprasad Vankayalapati , Alexis Mollard , Steven L. Warner , Sunil Sharma
- Applicant Address: US UT Salt Lake City
- Assignee: University of Utah Research Foundation
- Current Assignee: University of Utah Research Foundation
- Current Assignee Address: US UT Salt Lake City
- Agency: Seed IP Law Group PLLC
- Main IPC: C07D239/42
- IPC: C07D239/42 ; C07D239/48 ; A61K31/506 ; C07D401/12 ; C07D403/12
Abstract:
In one aspect, the invention relates to substituted N-phenylpyrimidin-2-amine analogs, derivatives thereof, and related compounds, which are useful as inhibitors of Axl kinase; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of using the compounds and compositions for treating disorders associated with dysfunction of the Axl kinase. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
Public/Granted literature
- US20120283261A1 SUBSTITUTED N-PHENYLPYRIMIDIN-2-AMINE ANALOGS AS INHIBITORS OF THE AXL KINASE Public/Granted day:2012-11-08
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