Invention Grant
- Patent Title: Inhibitors of cyclophilins and uses thereof
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Application No.: US14186432Application Date: 2014-02-21
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Publication No.: US08901295B2Publication Date: 2014-12-02
- Inventor: Jean-Francois Guichou , Lionel Colliandre , Hakim Ahmed-Belkacem , Jean-Michel Pawlotsky
- Applicant: Institut National de la Sante et de la Recherche Medicale (INSERM)
- Applicant Address: FR Paris FR Montpellier FR Creteil FR Paris FR Paris
- Assignee: Institut National de la Sante et de la Recherche Medicale (INSERM),Universite Montpellier 1,Universite Paris-EST Creteil val de Marne,Assistance Publique-Hopitaux de Paris,Centre National de la Recherche Scientifique
- Current Assignee: Institut National de la Sante et de la Recherche Medicale (INSERM),Universite Montpellier 1,Universite Paris-EST Creteil val de Marne,Assistance Publique-Hopitaux de Paris,Centre National de la Recherche Scientifique
- Current Assignee Address: FR Paris FR Montpellier FR Creteil FR Paris FR Paris
- Agency: Whitham Curtis Christofferson & Cook, PC
- Priority: EP09306294 20091221
- Main IPC: C07D207/06
- IPC: C07D207/06 ; C07D211/42 ; C07D213/72 ; C07D223/04 ; C07D231/12 ; C07D235/16 ; C07D239/26 ; C07D249/08 ; C07D261/08 ; C07D295/155 ; C07D307/81 ; C07D309/06 ; C07D317/60 ; C07D319/18 ; C07D401/06 ; C07D413/06 ; C07D307/52 ; C07D295/13 ; C07D209/08 ; C07D213/74 ; C07D277/40 ; C07D285/135 ; C07D317/58 ; C07D401/12 ; C07D231/20 ; C07D213/40 ; C07D233/32 ; C07D231/04 ; C07D413/04 ; C07D401/04 ; C07C275/24 ; C07D211/56 ; C07D295/192 ; C07D513/04 ; C07D405/12 ; C07D211/60 ; C07D307/14 ; C07D241/18 ; C07C335/12 ; C07D295/135 ; C07D413/12 ; C07D309/04 ; C07D213/73 ; C07D211/46 ; C07D403/06 ; C07C291/02 ; C07D295/08 ; C07D211/16 ; C07D401/14 ; C07D207/10 ; C07C307/06 ; C07D239/92 ; C07D213/30 ; C07C323/59 ; C07D235/14
Abstract:
The present invention relates to a compound of formula (I): wherein: n is 0, 1 or 2; A is in particular CH or N; X is in particular CO, SO2, CS, and R1 is in particular H, R2 is a group of formula NR3R4 or OR5, R3 and R4 being in particular H, and R5 an alkyl group, R6 is in particular H or an alkyl group, and R7 is in particular an aryl group, for its use in the prevention and/or the treatment of viral pathologies or infections.
Public/Granted literature
- US20140179687A1 New Inhibitors of Cyclophilins and Uses Thereof Public/Granted day:2014-06-26
Information query
