Invention Grant
- Patent Title: Chemical compounds 251
- Patent Title (中): 化合物251
-
Application No.: US13000138Application Date: 2009-07-02
-
Publication No.: US08901307B2Publication Date: 2014-12-02
- Inventor: Leslie Dakin , James Edward Dowling , Michelle Lamb , Jon Read , Xiaolan Zheng
- Applicant: Leslie Dakin , James Edward Dowling , Michelle Lamb , Jon Read , Xiaolan Zheng
- Applicant Address: SE Sodertalje
- Assignee: AstraZeneca AB
- Current Assignee: AstraZeneca AB
- Current Assignee Address: SE Sodertalje
- International Application: PCT/GB2009/050773 WO 20090702
- International Announcement: WO2010/001169 WO 20100107
- Main IPC: C07D417/10
- IPC: C07D417/10 ; A61K31/454 ; C07D417/14 ; A61K31/427 ; C07D277/34 ; C07D417/06 ; A61K31/426
Abstract:
The invention relates to chemical compounds of formula (I), and salts thereof. In some embodiments, the invention relates to inhibitors or modulators of PIM-1 and/or PIM-2, and/or PIM-3 protein kinase activity or enzyme function. In still further embodiments, the invention relates to pharmaceutical compositions comprising compounds disclosed herein, and their use in the prevention and treatment of PIM kinase related conditions and diseases, preferably cancer.
Public/Granted literature
- US20110218182A1 CHEMICAL COMPOUNDS 251 Public/Granted day:2011-09-08
Information query
