A first path for forwarding an I/O request from a host device to a disk in a disk array is identified. The first path includes two endpoints (a first initiator endpoint on the host device and a first target endpoint on the disk array) separated by a storage area network. In response to an indication that the first path is non-functional, a second path to the disk for the I/O request is identified as an alternative to the first path. The second path includes a second initiator endpoint and a second target endpoint and is identified by selecting a path from among those paths that have at least one endpoint that is different from the two endpoints of the first path.