The present disclosure provides a coordinated scheduling method and system in coordinated multi-point transmission. The method includes: a central control cell of a region determines priorities of users to be scheduled in all coordinated cells according to user information from other coordinated cells in the region; the central control cell schedules users in each coordinated cell according to the determined priorities and informs a corresponding coordinated cell of the information on a user that is finally determined to be scheduled; and after receiving the scheduling information from the central control cell, the corresponding coordinated cell schedules a user in corresponding time and frequency resources. The present disclosure ensures performance of a user with the highest priority, further, considering the performance of the whole system, scheduling is performed in a scheduling stage according to a principle that the subsequent users to be scheduled should cause as little interference on the scheduled users as possible, therefore, the interference between scheduled users is effectively reduced, and the capacity of the system is greatly increased.