Invention Grant
US08906366B2 Methods for preparing factor X, activated factor X, inactivated factor X and inactivated factor Xa, and pharmaceutical compositions comprising same
有权
制备因子X，活化因子X，灭活因子X和灭活因子Xa的方法和包含其的药物组合物
- Patent Title: Methods for preparing factor X, activated factor X, inactivated factor X and inactivated factor Xa, and pharmaceutical compositions comprising same
- Patent Title (中): 制备因子X，活化因子X，灭活因子X和灭活因子Xa的方法和包含其的药物组合物
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Application No.: US12601930Application Date: 2008-05-29
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Publication No.: US08906366B2Publication Date: 2014-12-09
- Inventor: Joanne Lloyd , Peter Feldman
- Applicant: Joanne Lloyd , Peter Feldman
- Applicant Address: GB Watford
- Assignee: NHS Blood and Transplant
- Current Assignee: NHS Blood and Transplant
- Current Assignee Address: GB Watford
- Agency: Armstrong Teasdale LLP
- Priority: GB0710321.1 20070530
- International Application: PCT/GB2008/001810 WO 20080529
- International Announcement: WO2008/145989 WO 20081204
- Main IPC: A61K38/48
- IPC: A61K38/48 ; A61P7/02 ; C12N9/48 ; C12N9/74
Abstract:
Methods for preparing Factor X, activated Factor X, inactivated factor X and inactivated factor Xa, compositions comprising Factor X and Factor Xa, inactivated Factor X and inactivated Factor Xa and methods of medical treatment using Factor X, Factor Xa, activated Factor X and inactivated Factor Xa are disclosed. The preparation methods comprise a chromatography step using an immobilised metal ion affinity chromatography substrate.
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