Invention Grant
- Patent Title: High level expression of recombinant toxin proteins
- Patent Title (中): 重组毒素蛋白的高水平表达
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Application No.: US13952484Application Date: 2013-07-26
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Publication No.: US08906636B2Publication Date: 2014-12-09
- Inventor: Diane M. Retallack , Lawrence Chew
- Applicant: Pfenex Inc.
- Applicant Address: US CA San Diego
- Assignee: Pfenex Inc.
- Current Assignee: Pfenex Inc.
- Current Assignee Address: US CA San Diego
- Agency: Wilson Sonsini Goodrich & Rosati
- Main IPC: C12N9/10
- IPC: C12N9/10 ; C12P21/00 ; G01N33/573 ; C12N15/78 ; C12P21/02 ; C07K14/34
Abstract:
The present invention relates to the field of recombinant toxin protein production in bacterial hosts. In particular, the present invention relates to production processes for obtaining high levels of a recombinant CRM197, Diphtheria Toxin, Pertussis Toxin, Tetanus Toxoid Fragment C, Cholera Toxin B, Cholera holotoxin, and Pseudomonas Exotoxin A, from a bacterial host.
Public/Granted literature
- US20140051093A1 HIGH LEVEL EXPRESSION OF RECOMBINANT TOXIN PROTEINS Public/Granted day:2014-02-20
Information query
