Invention Grant
- Patent Title: Phosphoinositide 3-kinase inhibitors with a zinc binding moiety
- Patent Title (中): 具有锌结合部分的磷酸肌醇3-激酶抑制剂
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Application No.: US13892373Application Date: 2013-05-13
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Publication No.: US08906909B2Publication Date: 2014-12-09
- Inventor: Xiong Cai , Haixiao Zhai , Chengjung Lai , Changgeng Qian
- Applicant: Curis, Inc.
- Applicant Address: US MA Lexington
- Assignee: Curis, Inc.
- Current Assignee: Curis, Inc.
- Current Assignee Address: US MA Lexington
- Agency: Elmore Patent Law Group, P.C.
- Agent Edgar W. Harlan; Carolyn S. Elmore, Esq.
- Main IPC: A61K31/535
- IPC: A61K31/535 ; C07D413/14 ; C07D495/04

Abstract:
The instant application relates to deazapurines, thienopyrimidines and furopyrimidines with zinc-binding moiety based derivatives and their use in the treatment of phosphoinositide 3-kinase related diseases and disorders such as cancer. The instant application further relates to the treatment of histone deacetylase related disorders and diseases related to both histone deacetylase and phosphoinositide 3-kinase.
Public/Granted literature
- US20140155595A1 PHOSPHOINOSITIDE 3-KINASE INHIBITORS WITH A ZINC BINDING MOIETY Public/Granted day:2014-06-05
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