Invention Grant
- Patent Title: Antibacterial cyclopenta[c]pyrrole substituted 3,4-dihydro-1H-[1,8]naphthyridinones
-
Application No.: US14237862Application Date: 2012-08-10
-
Publication No.: US08906923B2Publication Date: 2014-12-09
- Inventor: Jerôme Emile Georges Guillemont , David Francis Alain Lançois , Magali Madeleine Simone Motte , Anil Koul , Wendy Mia Albert Balemans , Eric Pierre Alexandre Arnoult
- Applicant: Jerôme Emile Georges Guillemont , David Francis Alain Lançois , Magali Madeleine Simone Motte , Anil Koul , Wendy Mia Albert Balemans , Eric Pierre Alexandre Arnoult
- Applicant Address: IE Little Island, Co Cork
- Assignee: Janssen R&D Ireland
- Current Assignee: Janssen R&D Ireland
- Current Assignee Address: IE Little Island, Co Cork
- Priority: EP11177119 20110810
- International Application: PCT/EP2012/065733 WO 20120810
- International Announcement: WO2013/021054 WO 20130214
- Main IPC: C07D471/00
- IPC: C07D471/00 ; C07D487/00 ; C07D471/02 ; A61K31/50 ; A61K31/495 ; A61K31/44
![Antibacterial cyclopenta[c]pyrrole substituted 3,4-dihydro-1H-[1,8]naphthyridinones](/abs-image/US/2014/12/09/US08906923B2/abs.jpg.150x150.jpg)
Abstract:
The present invention is related to novel compounds of formula (I) that inhibit the activity of the FabI enzyme which are therefore useful in the treatment of bacterial infections. It further relates to pharmaceutical compositions comprising these compounds, and chemical processes for preparing these compounds.
Public/Granted literature
- US20140171451A1 Antibacterial cyclopenta[c]pyrrole substituted 3,4-dihydro-1H-[1,8]naphthyridinones Public/Granted day:2014-06-19
Information query