Invention Grant
US08906924B2 (heterocycle/tetrahydropyridine)-(piperazinyl)-1-alcanone and (heterocycle/dihydropyrrolidine)-(piperazinyl)-1-alcanone derivatives, and use thereof as p75 inhibitors
有权
（杂环/四氢吡啶） - （哌嗪基）-1-阿卡酮和（杂环/二氢吡咯烷） - （哌嗪基）-1-阿糖酮衍生物，及其作为p75抑制剂的用途
- Patent Title: (heterocycle/tetrahydropyridine)-(piperazinyl)-1-alcanone and (heterocycle/dihydropyrrolidine)-(piperazinyl)-1-alcanone derivatives, and use thereof as p75 inhibitors
- Patent Title (中): （杂环/四氢吡啶） - （哌嗪基）-1-阿卡酮和（杂环/二氢吡咯烷） - （哌嗪基）-1-阿糖酮衍生物，及其作为p75抑制剂的用途
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Application No.: US13945478Application Date: 2013-07-18
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Publication No.: US08906924B2Publication Date: 2014-12-09
- Inventor: Marco Baroni , Francoise Bono , Sandrine Delbary-Gossart , Valentina Vercesi
- Applicant: Sanofi
- Applicant Address: FR Paris
- Assignee: Sanofi
- Current Assignee: Sanofi
- Current Assignee Address: FR Paris
- Agent Kelly L. Bender
- Priority: FR0906025 20091214
- Main IPC: A61K31/50
- IPC: A61K31/50 ; A61K31/501 ; C07D405/04 ; C07D487/08 ; C07D409/04 ; C07D401/04 ; C07D401/14 ; C07D495/04 ; C07D409/14 ; C07D405/14
Abstract:
The disclosure relates to (heterocycle-tetrahydropyridine)(piperazinyl)-1-alkanone and (heterocycle-dihydropyrrolidine)(piperazinyl)-1-alkanone derivatives of formula (I): wherein A, B, m, n, W, and R2 are as defined in the disclosure; to the methods of preparing said derivatives, and to the therapeutic uses thereof.
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