Invention Grant
US08907095B2 Bicyclic heterocycle derivatives and their use as modulators of the activity of GPR119
有权
双环杂环衍生物及其作为GPR119活性调节剂的用途
- Patent Title: Bicyclic heterocycle derivatives and their use as modulators of the activity of GPR119
- Patent Title (中): 双环杂环衍生物及其作为GPR119活性调节剂的用途
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Application No.: US12739531Application Date: 2008-10-20
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Publication No.: US08907095B2Publication Date: 2014-12-09
- Inventor: Yan Xia , Craig D. Boyle , William J. Greenlee , Samuel Chackalamannil , Charles Lee Jayne
- Applicant: Yan Xia , Craig D. Boyle , William J. Greenlee , Samuel Chackalamannil , Charles Lee Jayne
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Anna L. Cocuzzo; Catherine D. Fitch
- International Application: PCT/US2008/080462 WO 20081020
- International Announcement: WO2009/055331 WO 20090430
- Main IPC: C07D221/02
- IPC: C07D221/02 ; A61K31/439 ; C07D451/14 ; C07D491/08 ; C07D495/08 ; C07D471/08 ; C07D451/06 ; C07D487/08 ; C07D401/14 ; C07D498/08
Abstract:
The present invention relates to Bicyclic Heterocycle Derivatives, compositions comprising a Bicyclic Heterocycle Derivative, and methods of using the Bicyclic Heterocycle Derivatives for treating or preventing obesity, diabetes, a metabolic disorder, a cardiovascular disease or a disorder related to the activity of GPR119 in a patient.
Public/Granted literature
- US20110212938A1 BICYCLIC HETEROCYCLE DERIVATIVES AND THEIR USE AS MODULATORS OF THE ACTIVITY OF GPR119 Public/Granted day:2011-09-01
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