A pixel array substrate includes a substrate, a plurality of center pixel units, a plurality of edge pixel units, at least one conductive pattern, at least one passive electrode and a driving circuit. The substrate includes a main display area and a sub-display area around the main display area. The center pixel units and the edge pixel units are arrayed in the main display area. The conductive pattern and the passive electrode are disposed in the sub-display area, and the conductive pattern is electrically connected to the driving circuit and the passive electrode. The driving circuit is electrically connected to the edge pixel units and the passive electrode and configured to output a plurality of edge pixel signals to the edge pixel units and the passive electrode. A display panel using the pixel array substrate is provided. The pixel array substrate and the display panel have an advantage of increasing display area.