Systems and methods for detecting and mitigating interference between from a first wireless time division duplex (TDD) communications device and a second wireless TDD communications device includes processing quality-indicator reports received from the first TDD device to determine if reception at the first TDD device has experienced interference from the second TDD device. Such interference at the first TDD device may indicate that the first TDD device may also cause interference to reception at the second TDD device. Accordingly, to mitigate the possible interference from the first TDD device, an uplink configuration of the first TDD base station may be adjusted. The adjustment of the uplink configuration may include configuring reception of data packets at the first TDD base station from the first TDD device in accordance with an interference-free time interval, an unprotected time interval, or a specific portion of an associated frequency band.