Invention Grant
- Patent Title: Antigen binding proteins to oncostatin M (OSM)
- Patent Title (中): 抗原结合蛋白与制瘤素M（OSM）
-
Application No.: US13989191Application Date: 2011-11-21
-
Publication No.: US08916695B2Publication Date: 2014-12-23
- Inventor: Gary Peter Bembridge , Chun-Wa Chung , Maria Feeney , Susannah Karen Ford , Ian Kirby , Ruth McAdam
- Applicant: Gary Peter Bembridge , Chun-Wa Chung , Maria Feeney , Susannah Karen Ford , Ian Kirby , Ruth McAdam
- Applicant Address: GB
- Assignee: Glaxo Group Limited
- Current Assignee: Glaxo Group Limited
- Current Assignee Address: GB
- Agent Jason C. Fedon; William T. Han
- International Application: PCT/EP2011/070604 WO 20111121
- International Announcement: WO2012/069433 WO 20120531
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C07K16/00 ; C07K16/24
Abstract:
The present invention concerns antigen binding proteins and fragments thereof which specifically bind Oncostatin M (OSM), particularly human OSM (hOSM) and which inhibit the binding of OSM to the gp130 receptor but does not directly interact with site II residues. The invention also concerns a method of humanizing antibodies. Further disclosed are pharmaceutical compositions, screening and medical treatment methods.
Public/Granted literature
- US20130251724A1 ANTIGEN BINDING PROTEINS TO ONCOSTATIN M (OSM) Public/Granted day:2013-09-26
Information query
