A system for managing drug labeling information includes a repository comprising a network accessible database, the repository having an upload portion and a download portion, the repository being accessible to a plurality of users via client computers coupled to a wide area network. The repository includes drug labeling information on a plurality of drugs stored therein. The upload portion of the repository is accessible by a first set of users while the download portion of the repository is accessible by a second set of users. In one preferred aspect of the invention, drug manufactures are able to upload new or revised PDF files containing drug labeling information. The new or revised PDF files are then available for download by pharmacists or other authorized users.