Invention Grant
US08926965B2 Nucleic acid encoding superoxide dismutase variants and methods of use thereof
有权
编码超氧化物歧化酶变体的核酸及其使用方法
- Patent Title: Nucleic acid encoding superoxide dismutase variants and methods of use thereof
- Patent Title (中): 编码超氧化物歧化酶变体的核酸及其使用方法
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Application No.: US13908584Application Date: 2013-06-03
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Publication No.: US08926965B2Publication Date: 2015-01-06
- Inventor: Danica Chen , Xiaolei Qiu
- Applicant: The Regents of the University of California
- Applicant Address: US CA Oakland
- Assignee: The Regents of the University of California
- Current Assignee: The Regents of the University of California
- Current Assignee Address: US CA Oakland
- Agency: Bozicevic, Field & Francis LLP
- Agent Paula A. Borden
- Main IPC: A61K38/44
- IPC: A61K38/44 ; C07H21/04 ; C12N1/20 ; C12N1/00 ; C12N15/00 ; C12N5/00 ; C12N5/07 ; C12N9/02 ; C12Q1/26 ; A61K38/50 ; A61K31/7088 ; A61K38/17
Abstract:
The present disclosure provides variant superoxide dismutase polypeptides, compositions comprising the polypeptides, and nucleic acids comprising nucleotide sequences encoding the polypeptides. The present disclosure provides methods of reducing oxidative damage in a cell, tissue, or organ. The present disclosure provides methods of identifying agents that increase superoxide dismutase activity.
Public/Granted literature
- US20140017221A1 Superoxide Dismutase Variants and Methods of Use Thereof Public/Granted day:2014-01-16
Information query
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