Invention Grant
US08926981B2 Methods of using chimeric receptors to identify autoimmune disease
有权
使用嵌合受体鉴定自身免疫疾病的方法
- Patent Title: Methods of using chimeric receptors to identify autoimmune disease
- Patent Title (中): 使用嵌合受体鉴定自身免疫疾病的方法
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Application No.: US13611819Application Date: 2012-09-12
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Publication No.: US08926981B2Publication Date: 2015-01-06
- Inventor: James L. Brown
- Applicant: James L. Brown
- Applicant Address: US OH Athens
- Assignee: Diagnostic Hybrids, Inc.
- Current Assignee: Diagnostic Hybrids, Inc.
- Current Assignee Address: US OH Athens
- Agency: Medlen & Carroll, LLP
- Main IPC: C07H21/02
- IPC: C07H21/02 ; C07H21/04 ; C12N15/00 ; C12N5/00 ; C12N5/02 ; C12N5/07 ; C12N5/10 ; C07K1/00 ; C07K14/00 ; C07K17/00 ; A61K39/00 ; G01N33/564 ; C07K14/72
Abstract:
The present invention provides methods and compositions useful in the diagnosis and management of autoimmune diseases. In particular, the present invention provides improved methods and compositions for the diagnosis and management of Graves' disease. The methods of the present invention not only avoids the need for radioactivity and are much simpler, economical, and rapid than methods traditionally used for the diagnosis of Graves' disease, but also improve upon the sensitivity and detection abilities of previous luciferase-based autoantibody detection assays.
Public/Granted literature
- US20130059312A1 Methods Of Using Chimeric Receptors to Identify Autoimmune Disease Public/Granted day:2013-03-07
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