Invention Grant
US08926986B2 Use of saccharides cross-reactive with Bacillus anthracis spore glycoprotein as a vaccine against anthrax
有权
使用与炭疽芽孢杆菌孢子糖蛋白交叉反应的糖作为针对炭疽的疫苗
- Patent Title: Use of saccharides cross-reactive with Bacillus anthracis spore glycoprotein as a vaccine against anthrax
- Patent Title (中): 使用与炭疽芽孢杆菌孢子糖蛋白交叉反应的糖作为针对炭疽的疫苗
-
Application No.: US13909992Application Date: 2013-06-04
-
Publication No.: US08926986B2Publication Date: 2015-01-06
- Inventor: Joanna Kubler-Kielb , Evguenii Vinogradov , Rachel Schneerson , Haijing Hu , Stephen H. Leppla , John B. Robbins
- Applicant: The United States of America as Represented by the Secretary of the Department of Health and Human Services , National Research Council of Canada
- Applicant Address: CA Ottawa, ON US DC Washington
- Assignee: National Research Council of Canada,The United States of America, as represented by the Secretary of the Department of Health and Human Services
- Current Assignee: National Research Council of Canada,The United States of America, as represented by the Secretary of the Department of Health and Human Services
- Current Assignee Address: CA Ottawa, ON US DC Washington
- Agency: Klarquist Sparkman, LLP
- Main IPC: A61K39/385
- IPC: A61K39/385 ; A61K47/48 ; C07H3/06 ; A61K39/02 ; A61K39/104 ; A61K39/00
Abstract:
Provided are immunogenic compositions and methods for eliciting an immune response against B. anthracis and other bacteria that contain 3-methyl-3-hydroxybutyrate- or 3-hydroxybutryate-substituted saccharides. Conjugates of 3-methyl-3-hydroxybutyrate- or 3-hydroxybutryate-substituted saccharides elicit an effective immune response against B. anthracis spores in mammalian hosts to which the conjugates are administered.
Public/Granted literature
Information query
