Invention Grant
- Patent Title: Methods and compositions using Listeria for enhancing immunogenicity by prime boost
- Patent Title (中): 利用李斯特菌提高免疫原性的方法和组合
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Application No.: US12374288Application Date: 2007-07-17
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Publication No.: US08926993B2Publication Date: 2015-01-06
- Inventor: Thomas W. Dubensky, Jr. , Dirk G. Brockstedt , Meredith Leong , Keith S. Bahjat
- Applicant: Thomas W. Dubensky, Jr. , Dirk G. Brockstedt , Meredith Leong , Keith S. Bahjat
- Applicant Address: US CA Berkeley
- Assignee: Aduro Biotech
- Current Assignee: Aduro Biotech
- Current Assignee Address: US CA Berkeley
- Agency: Acuity Law Group, P.C.
- Agent Michael A. Whittaker
- International Application: PCT/US2007/016290 WO 20070717
- International Announcement: WO2008/094188 WO 20080807
- Main IPC: A61K39/00
- IPC: A61K39/00
Abstract:
Provided herein are prime-boost regimens and materials used therein. The prime-boost regimens enhance the immune response to a target antigen. The vaccines used for boost are comprised of recombinant attenuated metabolically active Listeria that encodes an expressible antigen that is cross-reactive with the target antigen. In some examples, the immune response is a cellular immune response.
Public/Granted literature
- US20100233212A1 METHODS AND COMPOSITIONS USING LISTERIA FOR ENHANCING IMMUNOGENICITY BY PRIME BOOST Public/Granted day:2010-09-16
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