Invention Grant
- Patent Title: ABT-263 capsule
- Patent Title (中): ABT-263胶囊
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Application No.: US12974154Application Date: 2010-12-21
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Publication No.: US08927009B2Publication Date: 2015-01-06
- Inventor: Ping Tong , Deliang Zhou , Geoff G. Z. Zhang , Katherine R. Heemstra , Cristina M. Fischer , Nathaniel D. Catron , Eric A. Schmitt , Yeshwant D. Sanzgiri
- Applicant: Ping Tong , Deliang Zhou , Geoff G. Z. Zhang , Katherine R. Heemstra , Cristina M. Fischer , Nathaniel D. Catron , Eric A. Schmitt , Yeshwant D. Sanzgiri
- Applicant Address: US IL North Chicago
- Assignee: AbbVie Inc.
- Current Assignee: AbbVie Inc.
- Current Assignee Address: US IL North Chicago
- Main IPC: A61K9/48
- IPC: A61K9/48 ; A61K31/5377 ; A61K47/14 ; A61K47/24

Abstract:
A pharmaceutical capsule comprises a shell having encapsulated therewithin a liquid solution of ABT-263 or a pharmaceutically acceptable salt thereof in a substantially non-ethanolic carrier that comprises as pharmaceutically acceptable excipients (a) at least one phospholipid, (b) at least one solubilizing agent for the at least one phospholipid, selected from the group consisting of glycols, glycerides and mixtures thereof, (c) at least one non-phospholipid surfactant and (d) at least one sulfur-containing antioxidant. The capsule is useful in treatment of a disease characterized by overexpression of one or more anti-apoptotic Bcl-2 family proteins, for example cancer.
Public/Granted literature
- US20110159085A1 ABT-263 CAPSULE Public/Granted day:2011-06-30
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