Invention Grant
US08927025B2 Alcohol-resistant metoprolol-containing extended-release oral dosage forms 有权
耐醇美托洛尔延长释放口服剂型

  • Patent Title: Alcohol-resistant metoprolol-containing extended-release oral dosage forms
  • Patent Title (中): 耐醇美托洛尔延长释放口服剂型
  • Application No.: US13721128
    Application Date: 2011-05-09
  • Publication No.: US08927025B2
    Publication Date: 2015-01-06
  • Inventor: Ehab Hamed
  • Applicant: Ehab Hamed
  • Applicant Address: US MN Brooklyn Park
  • Assignee: Cima Labs Inc.
  • Current Assignee: Cima Labs Inc.
  • Current Assignee Address: US MN Brooklyn Park
  • International Application: PCT/US2011/035770 WO 20110509
  • International Announcement: WO2011/143120 WO 20111117
  • Main IPC: A61K9/16
  • IPC: A61K9/16 A61K9/20 A61K31/135
Alcohol-resistant metoprolol-containing extended-release oral dosage forms
Abstract:
This disclosure relates to an extended release oral dosage form comprising a matrix containing a viscosity modifier (but no lipid) and coated granules containing metoprolol or a pharmaceutically acceptable salt or solvate thereof. The dosage form has alcohol resistance and may also have crush resistance.
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