Invention Grant
- Patent Title: GNA11 mutations in melanoma
- Patent Title (中): 黑素瘤GNA11突变
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Application No.: US13504928Application Date: 2010-10-29
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Publication No.: US08927215B2Publication Date: 2015-01-06
- Inventor: Boris C. Bastian , Catherine D. Van Raamsdonk , Gregory S. Barsh
- Applicant: Boris C. Bastian , Catherine D. Van Raamsdonk , Gregory S. Barsh
- Applicant Address: US CA Oakland CA Vancouver, BC US CA Palo Alto
- Assignee: The Regents of the University of California,The University of British Columbia,The Board of Trustees of the Leland Stanford Junior University
- Current Assignee: The Regents of the University of California,The University of British Columbia,The Board of Trustees of the Leland Stanford Junior University
- Current Assignee Address: US CA Oakland CA Vancouver, BC US CA Palo Alto
- Agency: Kilpatrick Townsend & Stockton LLP
- International Application: PCT/US2010/054843 WO 20101029
- International Announcement: WO2011/053852 WO 20110505
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12P19/34
Abstract:
The present invention provides methods of detecting mutations in a GNA11 gene in a melanocytic neoplasm for diagnostic and prognostic purposes. The invention further provides methods of treating such melanocytic neoplasm by modulating the activity of the mutated GNA11 gene.
Public/Granted literature
- US20130058938A1 GNA11 MUTATIONS IN MELANOMA Public/Granted day:2013-03-07
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