Invention Grant
- Patent Title: Effects of alteration of expression of the MtfA gene and its homologs on the production of fungal secondary metabolites
- Patent Title (中): 改变MtfA基因及其同源物的表达对真菌次生代谢产物的影响
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Application No.: US14070094Application Date: 2013-11-01
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Publication No.: US08927255B2Publication Date: 2015-01-06
- Inventor: Ana M. Calvo-Byrd , Vellaisamy Ramamoorthy
- Applicant: Board of Trustees of Northern Illinois University
- Applicant Address: US IL DeKalk
- Assignee: Board of Trustees of Northern Illnois University
- Current Assignee: Board of Trustees of Northern Illnois University
- Current Assignee Address: US IL DeKalk
- Agency: Barnes & Thornburg LLP
- Agent Alice O. Martin
- Main IPC: C12N15/80
- IPC: C12N15/80 ; C12N1/14 ; C07K14/37 ; C12P37/00
Abstract:
Many fungal secondary metabolites are of industrial interest, such as antibiotics, while others are undesirable compounds such as mycotoxins. Overexpression of mtfA enhances production of fungal compounds with applications in the medical field, and overexpression or impaired mtfA expression decreases the production of compounds that negatively affect health/agriculture/economy such as mycotoxins.
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