Invention Grant
US08927278B2 Method for generating immunomodulatory cells, the cells prepared therefrom, and use thereof
有权
用于产生免疫调节细胞的方法，由其制备的细胞及其用途
- Patent Title: Method for generating immunomodulatory cells, the cells prepared therefrom, and use thereof
- Patent Title (中): 用于产生免疫调节细胞的方法，由其制备的细胞及其用途
-
Application No.: US13607976Application Date: 2012-09-10
-
Publication No.: US08927278B2Publication Date: 2015-01-06
- Inventor: Lin-Ju Yen , Ko-Jiunn Liu , Huey-Kang Sytwu
- Applicant: Lin-Ju Yen , Ko-Jiunn Liu , Huey-Kang Sytwu
- Applicant Address: TW Zhuan Township
- Assignee: National Health Research Institutes
- Current Assignee: National Health Research Institutes
- Current Assignee Address: TW Zhuan Township
- Agency: Baker & McKenzie LLP
- Main IPC: C12N5/0783
- IPC: C12N5/0783
Abstract:
The present invention develops a straightforward and rapid method for generating immunomodulatory cells from peripheral mononuclear cells, comprising treating peripheral mononuclear cells with a hepatocyte growth factor (HGF) to induce differentiation of the peripheral mononuclear cells into immunomodulatory leukocytes. The present invention also provides an immunomodulatory cell prepared according to this method. The present invention further provides a method for treating a disease caused by abnormal immune response comprising administering a HGF to a patient exhibiting the disease, inducing the patient's peripheral mononuclear cells to differentiate into immunomodulatory leukocytes, and modulating the abnormal immune response.
Public/Granted literature
- US20140073569A1 METHOD FOR GENERATING IMMUNOMODULATORY CELLS, THE CELLS PREPARED THEREFROM AND USE THEREOF Public/Granted day:2014-03-13
Information query
