Invention Grant
- Patent Title: Method for expanding hematopoietic stem cells
- Patent Title (中): 扩大造血干细胞的方法
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Application No.: US12608946Application Date: 2009-10-29
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Publication No.: US08927281B2Publication Date: 2015-01-06
- Inventor: Anthony E. Boitano , Michael Cooke , Shifeng Pan , Peter G. Schultz , John Tellew , Yongqin Wan , Xing Wang
- Applicant: Anthony E. Boitano , Michael Cooke , Shifeng Pan , Peter G. Schultz , John Tellew , Yongqin Wan , Xing Wang
- Applicant Address: BM Hamilton US CA La Jolla
- Assignee: IRM LLC,The Scripps Research Institute
- Current Assignee: IRM LLC,The Scripps Research Institute
- Current Assignee Address: BM Hamilton US CA La Jolla
- Agency: Genomics Institute of the Novartis Research Foundation
- Agent Chihang Amy Smith
- Main IPC: C12N5/00
- IPC: C12N5/00 ; C12N5/0789 ; C07D487/04 ; C07D473/34 ; C07D473/16 ; A61K38/00 ; C07D495/04
Abstract:
The present invention relates to compounds and compositions for expanding the number of CD34+ cells for transplantation. The invention further relates to a cell population comprising expanded hematopoietic stem cells (HSCs) and its use in autologous or allogeneic transplantation for the treatment of patients with inherited immunodeficient and autoimmune diseases and diverse hematopoietic disorders to reconstitute the hematopoietic cell lineages and immune system defense.
Public/Granted literature
- US20100183564A1 COMPOUNDS THAT EXPAND HEMATOPOIETIC STEM CELLS Public/Granted day:2010-07-22
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