Invention Grant
- Patent Title: Compositions and methods for inhibition of retroviruses
- Patent Title (中): 用于抑制逆转录病毒的组合物和方法
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Application No.: US12992797Application Date: 2009-05-18
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Publication No.: US08927510B2Publication Date: 2015-01-06
- Inventor: Nan Yan , Alan Engelman , Judy Lieberman
- Applicant: Nan Yan , Alan Engelman , Judy Lieberman
- Applicant Address: US MA Boston US MA Boston
- Assignee: Children's Medical Center Corporation,Dana-Farber Cancer Institute, Inc.
- Current Assignee: Children's Medical Center Corporation,Dana-Farber Cancer Institute, Inc.
- Current Assignee Address: US MA Boston US MA Boston
- Agent Mark J. FitzGerald; David S. Resnick; Ravinderjit Braich
- International Application: PCT/US2009/044339 WO 20090518
- International Announcement: WO2009/140676 WO 20091119
- Main IPC: C12N15/11
- IPC: C12N15/11 ; A61K31/00
Abstract:
Described herein are methods and compositions for the inhibition of retroviral integration and replication. The methods and compositions inhibit the activity of one or more components of the SET complex or base excision repair enzymes and induce autointegration of retroviral double-stranded nucleic acid.
Public/Granted literature
- US20110142854A1 COMPOSITIONS AND METHODS FOR INHIBITION OF RETROVIRUSES Public/Granted day:2011-06-16
Information query
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