Invention Grant
US08927511B2 Treatment of vascular endothelial growth factor (VEGF) related diseases by inhibition of natural antisense transcript to VEGF
有权
通过抑制VEGF的天然反义转录物治疗血管内皮生长因子（VEGF）相关疾病
- Patent Title: Treatment of vascular endothelial growth factor (VEGF) related diseases by inhibition of natural antisense transcript to VEGF
- Patent Title (中): 通过抑制VEGF的天然反义转录物治疗血管内皮生长因子（VEGF）相关疾病
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Application No.: US13132997Application Date: 2009-12-02
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Publication No.: US08927511B2Publication Date: 2015-01-06
- Inventor: Joseph Collard , Olga Khorkova Sherman
- Applicant: Joseph Collard , Olga Khorkova Sherman
- Assignee: CuRNA, Inc.
- Current Assignee: CuRNA, Inc.
- Agency: CuRNA, Inc.
- Agent Monte R. Browder
- International Application: PCT/US2009/066455 WO 20091202
- International Announcement: WO2010/065671 WO 20100610
- Main IPC: A61K48/00
- IPC: A61K48/00 ; C12Q1/68 ; A61K31/712 ; C12N15/113
Abstract:
Oligonucleotide compounds modulate expression and/or function of Vascular Endothelial Growth Factor (VEGF) polynucleotides and encoded products thereof. Methods for treating diseases associated with Vascular Endothelial Growth Factor (VEGF) comprise administering one or more Oligonucleotide compounds designed to inhibit the VEGF natural antisense transcript to patients.
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