Invention Grant
US08927515B2 Methods and compositions for the specific inhibition of androgen receptor by double-stranded RNA
有权
通过双链RNA特异性抑制雄激素受体的方法和组合物
- Patent Title: Methods and compositions for the specific inhibition of androgen receptor by double-stranded RNA
- Patent Title (中): 通过双链RNA特异性抑制雄激素受体的方法和组合物
-
Application No.: US13723623Application Date: 2012-12-21
-
Publication No.: US08927515B2Publication Date: 2015-01-06
- Inventor: Bob D. Brown , Henryk T. Dudek
- Applicant: Dicerna Pharmaceuticals, Inc.
- Applicant Address: US MA Watertown
- Assignee: Dicerna Pharmaceuticals, Inc.
- Current Assignee: Dicerna Pharmaceuticals, Inc.
- Current Assignee Address: US MA Watertown
- Agency: Edwards Wildman Palmer LLP
- Agent Christopher R. Cowles
- Main IPC: A61K31/70
- IPC: A61K31/70 ; C07H21/02 ; C07H21/04 ; C12N15/113 ; C12Q1/68 ; A61K31/713 ; A61K31/7105
Abstract:
This invention relates to compounds, compositions, and methods useful for reducing AR target RNA and protein levels via use of dsRNAs, e.g., Dicer substrate siRNA (DsiRNA) agents.
Public/Granted literature
- US20130131149A1 METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF ANDROGEN RECEPTOR BY DOUBLE-STRANDED RNA Public/Granted day:2013-05-23
Information query
