Invention Grant
US08927538B2 Carbazole linked pyrrolo[2,1-c][1,4]benzodiazefine hybrids as potential anticancer agents and process for the preparation thereof
有权
咔唑连接的吡咯并[2,1-c] [1,4]苯并二氮杂双环杂化物作为潜在的抗癌剂及其制备方法
![Carbazole linked pyrrolo[2,1-c][1,4]benzodiazefine hybrids as potential anticancer agents and process for the preparation thereof](/docs/US/2015-01-06/US08927538B2/abs.jpg.600x600.jpg)
- Patent Title: Carbazole linked pyrrolo[2,1-c][1,4]benzodiazefine hybrids as potential anticancer agents and process for the preparation thereof
- Patent Title (中): 咔唑连接的吡咯并[2,1-c] [1,4]苯并二氮杂双环杂化物作为潜在的抗癌剂及其制备方法
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Application No.: US13129465Application Date: 2010-12-03
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Publication No.: US08927538B2Publication Date: 2015-01-06
- Inventor: Ahmed Kamal , Rajesh V. C. R. N. C Shetti , Srinivasa K. Reddy , Adla Malla Reddy
- Applicant: Ahmed Kamal , Rajesh V. C. R. N. C Shetti , Srinivasa K. Reddy , Adla Malla Reddy
- Applicant Address: IN
- Assignee: Council of Scientific & Industrial Research
- Current Assignee: Council of Scientific & Industrial Research
- Current Assignee Address: IN
- Agency: Cowan, Liebowitz & Latman, P.C.
- Agent Mark Montague
- Priority: IN678/DEL/2010 20100322
- International Application: PCT/IB2010/003087 WO 20101203
- International Announcement: WO2011/117668 WO 20110929
- Main IPC: C07D487/04
- IPC: C07D487/04
![Carbazole linked pyrrolo[2,1-c][1,4]benzodiazefine hybrids as potential anticancer agents and process for the preparation thereof](/abs-image/US/2015/01/06/US08927538B2/abs.jpg.150x150.jpg)
Abstract:
The present invention provides a compound of general formulae A useful as potential antitumour agents against human cancer cell lines. The present invention further provides a process for the preparation of pyrrolo[2, 1-c][1,4]benzodiazepine hybrids of general formulae 6a-g, 10a-o, 14a-g and 18a-o.
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