Invention Grant
- Patent Title: Bicyclic antibiotics
- Patent Title (中): 双环抗生素
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Application No.: US14216486Application Date: 2014-03-17
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Publication No.: US08927542B2Publication Date: 2015-01-06
- Inventor: Berangere Gaucher , Franck Hubert Danel , Patrick Roussel
- Applicant: Basilea Pharmaceutica AG
- Applicant Address: CH Basel
- Assignee: Basilea Pharmaceutica AG
- Current Assignee: Basilea Pharmaceutica AG
- Current Assignee Address: CH Basel
- Priority: EP09151027 20090121
- Main IPC: C07D498/04
- IPC: C07D498/04 ; A61K31/536 ; A61K31/5365

Abstract:
The antibacterial compound of formula I wherein X1, X3; X4 and X6, each independently of the others, represents a nitrogen atom or CR2, with the proviso that at least one of X1, X3; X4 and X6 represents a nitrogen atom; X2 represents C—H, C—(C1-C6alkyl), C—(C1-C6alkoxy), C-halogen, C—COOH; X5 represents C—H or C—(C1-C6alkyl), C-halogen; A1, A2, A3, R1 and R4 represent various substituents, G represents aryl or heteroaryl, which is unsubstituted or substituted which compounds show good activity against pathogenic bacteria.
Public/Granted literature
- US20140221348A1 NOVEL BICYCLIC ANTIBIOTICS Public/Granted day:2014-08-07
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