Invention Grant
US08927560B2 4-Aza-2, 3-didehydropodophyllotoxin compounds and process for the preparation thereof
有权
4-氮杂-2,3-脱水鬼臼毒素化合物及其制备方法
- Patent Title: 4-Aza-2, 3-didehydropodophyllotoxin compounds and process for the preparation thereof
- Patent Title (中): 4-氮杂-2,3-脱水鬼臼毒素化合物及其制备方法
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Application No.: US13522219Application Date: 2011-03-25
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Publication No.: US08927560B2Publication Date: 2015-01-06
- Inventor: Kamal Ahmed , Suresh Paidakula , Ashwini Kumar Banala , Mallareddy Adla , Venkat Reddy Papagari , Rasheed Tamboli Jaki
- Applicant: Kamal Ahmed , Suresh Paidakula , Ashwini Kumar Banala , Mallareddy Adla , Venkat Reddy Papagari , Rasheed Tamboli Jaki
- Applicant Address: IN New Delhi
- Assignee: Council of Scientific & Industrial Research
- Current Assignee: Council of Scientific & Industrial Research
- Current Assignee Address: IN New Delhi
- Agency: Edwards Wildman Palmer LLP
- Agent Jeffrey D. Hsi
- Priority: IN2887/DEL/2010 20101206
- International Application: PCT/IB2011/000641 WO 20110325
- International Announcement: WO2012/076942 WO 20120614
- Main IPC: A61K31/505
- IPC: A61K31/505 ; A01N43/54 ; A01N43/42 ; A61K31/44 ; C07D491/00 ; C07D239/00 ; C07D471/00 ; C07D487/00 ; C07D261/20 ; C07D498/00 ; C07D491/04 ; C07D498/14 ; C07D498/04 ; C07D491/147 ; C07D513/04
Abstract:
The present invention provides 4-Aza-2,3-didehydropodophyllotoxin compound of general formula A (4a-4z and 4aa-4ae) as useful potential antitumour agents against human cancer cell lines. The present invention further provides a process for the synthesis of 4-Aza-2,3-didehydropodophyllotoxin compounds (4a-4z and 4aa-4ae).
Public/Granted literature
- US20130245048A1 4-AZA-2, 3-DIDEHYDROPODOPHYLLOTOXIN COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF Public/Granted day:2013-09-19
Information query
