Invention Grant
- Patent Title: Thiochromene derivatives as HIF hydroxylase inhibitors
- Patent Title (中): 硫代衍生物作为HIF羟化酶抑制剂
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Application No.: US13128620Application Date: 2009-11-11
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Publication No.: US08927591B2Publication Date: 2015-01-06
- Inventor: Wen-Bin Ho , Lee R. Wright , Eric D. Turtle , Craig Mossman , Lee A. Flippin
- Applicant: Wen-Bin Ho , Lee R. Wright , Eric D. Turtle , Craig Mossman , Lee A. Flippin
- Applicant Address: US CA San Francisco
- Assignee: Fibrogen, Inc.
- Current Assignee: Fibrogen, Inc.
- Current Assignee Address: US CA San Francisco
- Agency: Sheppard Mullin Richter & Hampton LLP
- International Application: PCT/US2009/064065 WO 20091111
- International Announcement: WO2010/056767 WO 20100520
- Main IPC: A61K31/382
- IPC: A61K31/382 ; C07D335/06 ; C07D409/04
Abstract:
The present invention relates to novel compounds, methods, and compositions capable of decreasing HIF hydroxylase enzyme activity, thereby increasing the stability and/or activity of hypoxia inducible factor (HIF).
Public/Granted literature
- US20110305776A1 THIOCHROMENE DERIVATIVES AS HIF HYDROXYLASE INHIBITORS Public/Granted day:2011-12-15
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