Invention Grant
- Patent Title: Fibronectin based scaffold domain proteins that bind IL-23
- Patent Title (中): 结合IL-23的基于纤连蛋白的支架结构域蛋白
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Application No.: US13579204Application Date: 2011-02-16
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Publication No.: US08927693B2Publication Date: 2015-01-06
- Inventor: Ruchira Dasgupta , Alex Bush , Lumelle Schneeweis , Linda Engle
- Applicant: Ruchira Dasgupta , Alex Bush , Lumelle Schneeweis , Linda Engle
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent Nickki L. Parlet
- International Application: PCT/US2011/024959 WO 20110216
- International Announcement: WO2011/103105 WO 20110825
- Main IPC: C07K14/00
- IPC: C07K14/00 ; C07K14/78 ; C12N15/10 ; A61K38/00
Abstract:
The present invention relates to fibronectin based scaffold domain protein that bind interleukin 23 (IL-23), specifically the p19 subunit of IL-23. The invention also relates to the use of the innovative proteins in therapeutic applications to treat autoimmune diseases. The invention further relates to cells comprising such proteins, polynucleotide encoding such proteins or fragments thereof, and to vectors comprising the polynucleotides encoding the innovative proteins.
Public/Granted literature
- US20130012436A1 FIBRONECTIN BASED SCAFFOLD DOMAIN PROTEINS THAT BIND IL-23 Public/Granted day:2013-01-10
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