Invention Grant
- Patent Title: JAK kinase modulating compounds and methods of use thereof
- Patent Title (中): JAK激酶调节化合物及其使用方法
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Application No.: US13645406Application Date: 2012-10-04
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Publication No.: US08927711B2Publication Date: 2015-01-06
- Inventor: Sunny Abraham , Qi Chao , Michael J. Hadd , Mark W. Holladay , Gang Liu , Eduardo Setti
- Applicant: Ambit Biosciences Corp.
- Applicant Address: US CA San Diego
- Assignee: Ambit Biosciences Corp.
- Current Assignee: Ambit Biosciences Corp.
- Current Assignee Address: US CA San Diego
- Agency: Jones Day
- Main IPC: C07D403/12
- IPC: C07D403/12 ; A61K31/5377 ; C07D401/14 ; A61K45/06 ; C07D405/14 ; A61K31/517
Abstract:
Provided herein are quinazoline compounds of formula (I): The compounds are useful for treatment of JAK kinase mediated diseases, including JAK2 kinase-, JAK3 kinase- or TYK2 kinase-mediated diseases. Also provided are pharmaceutical compositions comprising the compounds and methods of using the compounds and compositions.
Public/Granted literature
- US20130245014A1 JAK KINASE MODULATING COMPOUNDS AND METHODS OF USE THEREOF Public/Granted day:2013-09-19
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