Invention Grant
US08927728B2 Dipeptide acetylene conjugates and a method for photocleavage of double strand DNA by dipeptide acetylene conjugates
有权
二肽乙炔缀合物和通过二肽乙炔缀合物对双链DNA进行光切割的方法
- Patent Title: Dipeptide acetylene conjugates and a method for photocleavage of double strand DNA by dipeptide acetylene conjugates
- Patent Title (中): 二肽乙炔缀合物和通过二肽乙炔缀合物对双链DNA进行光切割的方法
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Application No.: US13465529Application Date: 2012-05-07
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Publication No.: US08927728B2Publication Date: 2015-01-06
- Inventor: Igor Alabugin , Wang-Yong Yang , Saumya Roy , Kemal Kaya , Qing-Xiang Sang
- Applicant: Igor Alabugin , Wang-Yong Yang , Saumya Roy , Kemal Kaya , Qing-Xiang Sang
- Applicant Address: US FL Tallahassee
- Assignee: The Florida State University Research Foundation, Inc.
- Current Assignee: The Florida State University Research Foundation, Inc.
- Current Assignee Address: US FL Tallahassee
- Agency: Armistrong Teasdale LLP
- Main IPC: C07D213/16
- IPC: C07D213/16 ; C07D213/56 ; C07D213/61 ; C07K5/062 ; C07K5/065 ; C07K5/068
Abstract:
Photoreactive DNA cleaving conjugate compounds are provided comprising a DNA cleaving moiety which comprises an aryl alkyne group and a polyfunctional pH-regulated DNA-binding moiety which comprises at least one or two amino groups.
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