Invention Grant
- Patent Title: Process for obtaining dronedarone
- Patent Title (中): 获得决奈达隆的方法
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Application No.: US13880162Application Date: 2011-10-18
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Publication No.: US08927743B2Publication Date: 2015-01-06
- Inventor: Ravindranath Vishnu Newadkar , Avinash Changdeo Gaikwad , Ajay Madhukar Harad
- Applicant: Ravindranath Vishnu Newadkar , Avinash Changdeo Gaikwad , Ajay Madhukar Harad
- Applicant Address: ES Barcelona
- Assignee: Laboratorios Lesvi, S.L.
- Current Assignee: Laboratorios Lesvi, S.L.
- Current Assignee Address: ES Barcelona
- Agency: Winstead PC
- Priority: EP10188336 20101021
- International Application: PCT/EP2011/068202 WO 20111018
- International Announcement: WO2012/052448 WO 20120426
- Main IPC: C07D307/80
- IPC: C07D307/80 ; C07D307/81
Abstract:
The present invention provides a process for obtaining dronedarone or salts thereof characterized in that in an organic phase comprising one or more non-polar solvents, 5-amino-3-[4-(3-di-n-butylaminopropoxy)benzoyl]-2-n-butyl-benzofuran is reacted with methane sulfonyl chloride without the addition of a base. The invention also provides a process for obtaining intermediates of dronedarone environmentally friendly and industrially viable.
Public/Granted literature
- US20130289287A1 PROCESS FOR OBTAINING DRONEDARONE Public/Granted day:2013-10-31
Information query
