Invention Grant
US08927750B2 Acyloxy- and phosphoryloxy-butadiene-Fe(CO)3 complexes as enzyme-triggered co-releasing molecules
有权
酰氧基和磷酰氧基 - 丁二烯-Fe（CO）3络合物作为酶触发的共释放分子
- Patent Title: Acyloxy- and phosphoryloxy-butadiene-Fe(CO)3 complexes as enzyme-triggered co-releasing molecules
- Patent Title (中): 酰氧基和磷酰氧基 - 丁二烯-Fe（CO）3络合物作为酶触发的共释放分子
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Application No.: US13020933Application Date: 2011-02-04
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Publication No.: US08927750B2Publication Date: 2015-01-06
- Inventor: Hans-Guenther Schmalz , Steffen Romanski , Sabine Amslinger , Benito Yard , Birgit Kraus
- Applicant: Hans-Guenther Schmalz , Steffen Romanski , Sabine Amslinger , Benito Yard , Birgit Kraus
- Applicant Address: DE Cologne DE Regensburg
- Assignee: Universitaet Zu Koeln,Universitaet Regensburg
- Current Assignee: Universitaet Zu Koeln,Universitaet Regensburg
- Current Assignee Address: DE Cologne DE Regensburg
- Agent Norman B. Thot
- Main IPC: C07F15/02
- IPC: C07F15/02 ; C07F7/08 ; C07F17/02 ; C07F7/18
Abstract:
The present invention provides acyloxy- and phosphoryloxy-butadiene-Fe(CO)3 complexes which can deliver carbon monoxide to a physiological target, wherein release of carbon monoxide can be enzymatically-triggered. The present invention also provides for methods of manufacturing the enzymatically-triggered carbon monoxide releasing molecules and methods for their use.
Public/Granted literature
- US20120202774A1 ACYLOXY- AND PHOSPHORYLOXY-BUTADIENE-FE(CO)3 COMPLEXES AS ENZYME-TRIGGERED CO-RELEASING MOLECULES Public/Granted day:2012-08-09
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