A power supply circuit is disclosed in embodiments of the present invention, which includes: a voltage output device, configured to generate an output voltage; a parasitic resistance, connected between an output end of the voltage output device and an external load, where two ends of the parasitic resistance generate a voltage drop; and a compensation circuit, connected to the output end of the voltage output device and configured to generate a compensation voltage, where the compensation voltage is loaded onto the voltage output device, so as to offset the voltage drop generated by the parasitic resistance, so that a voltage obtained at an input end of the load is roughly equal to the output voltage generated by the voltage output device. The circuit is applicable to improving load regulation of a power supply.