Propagation delay offsets of wireless signals are compensated. Compensation is accomplished through determination of an effective wireless signal propagation delay that accounts for signal path delay and propagation delay over the air. Such determination is based at least in part on statistical analysis of accurate location estimates of reference positions throughout a coverage sector or cell, and location estimates of the reference positions generated through time-of-flight (TOF) measurements of wireless signals. Determination of propagation or signal path delay offset also is attained iteratively based at least in part on reference location estimates and TOF location estimates. High-accuracy location estimates such as those obtained through global navigation satellite systems are employed as reference location estimates. Position of probes or wireless beacons, deployed throughout a sector or cell, also are employed as reference locations. Compensation of propagation delay offset improves accuracy of conventional TOF location estimates and radio network performance.