Invention Grant
US08929972B2 Arterial spin labeling MRI-based correction factor for improving quantitative accuracy of blood flow and volume images
有权
动脉自旋标记基于MRI的校正因子,用于提高血流量和体积图像的定量精度
- Patent Title: Arterial spin labeling MRI-based correction factor for improving quantitative accuracy of blood flow and volume images
- Patent Title (中): 动脉自旋标记基于MRI的校正因子,用于提高血流量和体积图像的定量精度
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Application No.: US12798280Application Date: 2010-03-31
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Publication No.: US08929972B2Publication Date: 2015-01-06
- Inventor: Roland Bammer , Greg Zaharchuk
- Applicant: Roland Bammer , Greg Zaharchuk
- Applicant Address: US CA Palo Alto
- Assignee: The Board of Trustees of the Leland Stanford Junior University
- Current Assignee: The Board of Trustees of the Leland Stanford Junior University
- Current Assignee Address: US CA Palo Alto
- Agency: Lumen Patent Firm
- Main IPC: A61B5/05
- IPC: A61B5/05 ; G01R33/563

Abstract:
Arterial spin labeling MRI is used to provide a patient specific correction factor to correct a image provided by a non-ASL imaging modality (e.g., DSC MRI). More specifically, a first blood flow image is taken using the non-ASL imaging modality, and a corresponding second blood flow image is taken with ASL. Some or all of the voxels in the first image are selected according to a predetermined selection method. A correction factor (CF) is computed to be the ratio of second image BF to first image BF averaged over the selected voxels. Thus, CF is the average of ASL/non-ASL blood flow over the selected voxels. This correction factor is applied to all voxels of an image equally, but can differ from patient to patient. This correction can be applied to one or more non-ASL blood flow images.
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