Invention Grant
US08929992B2 Method and system for determining settings for deep brain stimulation
有权
用于确定深部脑刺激设置的方法和系统
- Patent Title: Method and system for determining settings for deep brain stimulation
- Patent Title (中): 用于确定深部脑刺激设置的方法和系统
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Application No.: US13581484Application Date: 2011-02-25
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Publication No.: US08929992B2Publication Date: 2015-01-06
- Inventor: Emil Toader , Hubert Cécile François Martens , Michel Marcel Jose Decre , Franciscus Paulus Maria Budzelaar , Pieter Gerrit Blanken , David James Anderson
- Applicant: Emil Toader , Hubert Cécile François Martens , Michel Marcel Jose Decre , Franciscus Paulus Maria Budzelaar , Pieter Gerrit Blanken , David James Anderson
- Applicant Address: NL US MI Ann Arbor
- Assignee: Sapiens Steering Brain Stimulation B.V.,NeuroNexus Technologies Inc.
- Current Assignee: Sapiens Steering Brain Stimulation B.V.,NeuroNexus Technologies Inc.
- Current Assignee Address: NL US MI Ann Arbor
- Agency: Morgan, Lewis & Bockius LLP
- International Application: PCT/IB2011/050809 WO 20110225
- International Announcement: WO2011/107917 WO 20110909
- Main IPC: A61N1/36
- IPC: A61N1/36 ; A61N1/05 ; A61N1/00

Abstract:
A method and a control system (20) are provided for determining a relation between stimulation settings for a brain stimulation probe (10) and a corresponding V-field. The brain stimulation probe (10) comprises multiple stimulation electrodes (11). The V-field is an electrical field in brain tissue surrounding the stimulation electrodes (11). The method comprises sequentially applying a test current to n stimulation electrodes (11), n being a number between 2 and the number of stimulation electrodes (11) of the brain stimulation probe (10), for each test current at one of the n stimulation electrodes (11), measuring a resulting excitation voltage at m stimulation electrodes, m being a number between 2 and the number of stimulation electrodes (11) of the brain stimulation probe (10), from the stimulation settings and the measured excitation voltages, deriving an (m*{acute over (η)}) coupling matrix, an element (q, p) in the coupling matrix reflecting an amount of electrical impedance between two of the stimulation electrodes (11), and using the coupling matrix for determining the relation between the stimulation settings and the corresponding V-field.
Public/Granted literature
- US20130030500A1 Method and System for Determining Settings for Deep Brain Stimulation Public/Granted day:2013-01-31
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