The present publication describes a data transfer method and system in a digital sound reproduction system. The method comprises method steps for generating a digital audio stream for multiple channels in a host data source, e.g. a computer, the audio stream is formed by multiple consecutive samples, receiving the digital audio stream sent by the host data source through a digital data transmission network by several digital receivers each of which including a microcontroller with a clock, the receivers further including means for generating an audio signal. In accordance with the invention the host data source sends repeatedly a synchronization sample to at least one receiver, the receiver replies to the synchronization sample by a return sample, the host calculates a latency (T) for each receiver based on the sending time (Th1) of the synchronization sample and the reception time (Th2) of the return sample and the processing time (Tt1-Tt2) of the receiver, the host sends to the receiver information of the calculated latency (T) in combination with the time stamp the measurement time, based on this information the receiver adjusts the function of its clock, and the above synchronization steps are repeated continuously.