Invention Grant
US08932991B2 Planar support having an ultraflat surface and a device for detecting antigens comprising said planar support
有权
具有超平坦表面的平面载体和用于检测包含所述平面支撑物的抗原的装置
- Patent Title: Planar support having an ultraflat surface and a device for detecting antigens comprising said planar support
- Patent Title (中): 具有超平坦表面的平面载体和用于检测包含所述平面支撑物的抗原的装置
-
Application No.: US13808239Application Date: 2011-07-04
-
Publication No.: US08932991B2Publication Date: 2015-01-13
- Inventor: Francesca Ferrera , Vincenzo Ierardi , Gilberto Filaci , Enrico Millo , Gianluca Damonte , Francesco Indiveri , Ugo Valbusa
- Applicant: Francesca Ferrera , Vincenzo Ierardi , Gilberto Filaci , Enrico Millo , Gianluca Damonte , Francesco Indiveri , Ugo Valbusa
- Applicant Address: IT Genoa
- Assignee: Universita' Degli Studi de Genova
- Current Assignee: Universita' Degli Studi de Genova
- Current Assignee Address: IT Genoa
- Agency: Merchant & Gould P.C.
- Priority: ITTO2010A0577 20100705
- International Application: PCT/IB2011/052941 WO 20110704
- International Announcement: WO2012/004721 WO 20120112
- Main IPC: G01N33/68
- IPC: G01N33/68 ; G01N33/543 ; G01N33/552
Abstract:
A nanoarray or microarray of antibodies includes a planar surface having an ultraflat surface, which has a planar substrate functionalized with a first monolayer of linking molecules, preferably APTES molecules, and a second monolayer of small peptides of the general formula (I) capable of binding the Fc region of antibodies. The nanoarray or microarray includes capture antibodies immobilized on the planar support, preferably in the form of a matrix of spots, and is suitable to be used for detecting antigens in a biological sample by AFM imaging. Z—HN—R1—R2—R3—R4—R5—R6—NH—X—CO-G-COOH.
Public/Granted literature
Information query
IPC分类:
