Invention Grant
US08933071B2 Dimethyl fasudil for inducing polyploidization of megakaryocytes and for treating blood and bone marrow diseases and disorders
有权
二甲基法舒地尔诱导巨核细胞的多倍体化和治疗血液和骨髓疾病和病症
- Patent Title: Dimethyl fasudil for inducing polyploidization of megakaryocytes and for treating blood and bone marrow diseases and disorders
- Patent Title (中): 二甲基法舒地尔诱导巨核细胞的多倍体化和治疗血液和骨髓疾病和病症
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Application No.: US12613996Application Date: 2009-11-06
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Publication No.: US08933071B2Publication Date: 2015-01-13
- Inventor: John D. Crispino , Qiang Wen , Zan Huang , Andrew M. Stern , Robert J. Gould
- Applicant: John D. Crispino , Qiang Wen , Zan Huang , Andrew M. Stern , Robert J. Gould
- Applicant Address: US IL Evanston US MA Cambridge
- Assignee: Northwestern University,Massachusetts Institute of Technology
- Current Assignee: Northwestern University,Massachusetts Institute of Technology
- Current Assignee Address: US IL Evanston US MA Cambridge
- Agency: Andrus Intellectual Property Law, LLP
- Main IPC: A61K31/551
- IPC: A61K31/551 ; A61K31/5513

Abstract:
Disclosed are methods for inducing polyploidization of megakaryocyte cells and for promoting differentiation of megakaryocyte cells into platelet-producing cells. The methods may be utilized for treating blood and bone marrow diseases and disorders in a subject in need thereof and for identifying agents for treating blood and bone marrow diseases and disorders.
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