Invention Grant
- Patent Title: Process for preparing purified drug conjugates
- Patent Title (中): 制备纯化药物偶联物的方法
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Application No.: US13776097Application Date: 2013-02-25
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Publication No.: US08933205B2Publication Date: 2015-01-13
- Inventor: Yong Dai , Yong Wang , Shengjin Jin , Deborah H. Meshulam , Godfrey W. Amphlett
- Applicant: ImmunoGen, Inc.
- Applicant Address: US MA Waltham
- Assignee: ImmunoGen, Inc.
- Current Assignee: ImmunoGen, Inc.
- Current Assignee Address: US MA Waltham
- Agency: Leydig, Voit & Mayer, Ltd.
- Main IPC: C07K16/28
- IPC: C07K16/28 ; A61K47/48
Abstract:
The invention provides a process for preparing a cell-binding agent chemically coupled to a drug. The process comprises covalently attaching a linker to a cell-binding agent, a purification step, conjugating a drug to the cell-binding agent and a subsequent purification step.
Public/Granted literature
- US20130281678A1 PROCESS FOR PREPARING PURIFIED DRUG CONJUGATES Public/Granted day:2013-10-24
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