Invention Grant
- Patent Title: Use of protease nexin 1 inhibitors to reduce metastasis
- Patent Title (中): 使用蛋白酶nexin 1抑制剂来减少转移
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Application No.: US12746214Application Date: 2008-12-05
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Publication No.: US08933212B2Publication Date: 2015-01-13
- Inventor: Bérengère Fayard , Denis Monard
- Applicant: Bérengère Fayard , Denis Monard
- Applicant Address: CH Basel
- Assignee: Novartis Forschungsstiftung Zweigniederlassung Friedrich Miescher Institute for Biomedical Research
- Current Assignee: Novartis Forschungsstiftung Zweigniederlassung Friedrich Miescher Institute for Biomedical Research
- Current Assignee Address: CH Basel
- Agency: Hoxie & Associates LLC
- Priority: EP07122494 20071206
- International Application: PCT/EP2008/066879 WO 20081205
- International Announcement: WO2009/071660 WO 20090611
- Main IPC: C07H21/04
- IPC: C07H21/04
Abstract:
The present invention relates to a method of inhibiting metastasis comprising the administration of an inhibitor of protease nexin-1 (PN-1), characterized in that said inhibitor is administered at a therapeutical dosage that does not completely inhibit the expression and/or activity of PN-1.
Public/Granted literature
- US20100254976A1 USE OF PROTEASE NEXIN 1 INHIBITORS TO REDUCE METASTASIS Public/Granted day:2010-10-07
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