Invention Grant
- Patent Title: Phosphorus-containing group-substituted quinoline, its preparation process, medical composition containing the compounds and application
- Patent Title (中): 含磷基团取代喹啉，其制备方法，含有化合物和应用的医药组合物
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Application No.: US13982180Application Date: 2011-04-06
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Publication No.: US08933230B2Publication Date: 2015-01-13
- Inventor: Ziwei Yun , Hongtao Wang
- Applicant: Ziwei Yun , Hongtao Wang
- Applicant Address: CN Beijing
- Assignee: Beijing Konruns Pharmaceutical Co., Ltd.
- Current Assignee: Beijing Konruns Pharmaceutical Co., Ltd.
- Current Assignee Address: CN Beijing
- Agency: Stites & Harbison PLLC
- Agent Cong Ding
- Priority: CN201110036623 20110128
- International Application: PCT/CN2011/072456 WO 20110406
- International Announcement: WO2012/100459 WO 20120802
- Main IPC: C07D215/38
- IPC: C07D215/38 ; C07F9/60 ; A61K31/675 ; C07F9/6558
Abstract:
Phosphorus-containing group-substituted quinolines of formula (I) are provided in the present invention. The preparation process and application of the compound, and formulation comprising phosphorus-containing group-substituted quinolines are also disclosed. The compounds are protein kinase inhibitor and can be used for treating protein kinase abnormal activity-associated diseases, such as tumor, etc.
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